I just found out that 1 in 3 (!!!) people have a mutated gene

Please do your own research and ask your own doctors:

I just found out that 1 in 3 (!!!) people have a mutated gene which makes them unable to assimilate B vitamins.  These people have a tendency toward depression, insomnia, irritability, fatigue, and can lead to multiple health problems (cardiovascular, stroke, dementia, breast and prostrate and other cancers, etc.).  I am wondering if this could be a factor in autism as well.  If something called L-5-MTHF (the metabolically active form of folic acid) is also needed for detoxification of environmental toxins (mercury, lead, arsenic, etc.) as well as essential for brain development and maintenance and overall health…  Why isn’t this all over the news?!?

A simple blood test called “MTHFR” (methylfolate ruductase(?)) can tell you if you have this mutated gene and think of your children too.  If you do have this gene you take a supplement called deplin or 5-MTHF along with a B12 vitamin strip (think Listerene strips) that dissolves on your tongue.  Supposedly a B vitamin you swallow won’t be absorbed and utilized effectively.  Make sure you are taking high quality supplements.  You might also want to have your DHEA , hormones, vitamin B, and vitamin D levels tested as well.

So, do your own research.  I will too.  From what I’ve heard and read this deserves more attention and not to be brushed off.  I did find some information at www.drdebe.com/l-5-mthf-new-supplement-that-could-save-your-life.html  so that can be a starting point if you are interested.  (*I do not know Dr. Debe and am not in any way affiliated–I had just found out about this gene and was researching it and this website came up on google.)  So be your own researcher and maybe we can change the world in a positive way!


I just googled “autism health blog mthf” more info and I found http://findingtherootcause.blogspot.com and she lists a blog www.itsnotmental.blogspot.com.

Addendum:  02/11/2012

I just spoke with my doctor and she said that she had only tested for 2 of the mutated genes (one of which I had) and that she did not test me for the other 40 or so genes that could be mutated.  I did not notice a huge difference when I was taking the 5-MTHF supplement and so she has decided to put me on Deplin to help me assimilate B vitamins because it is more potent.  Who knows, I guess I’ll just have to wait and see if it makes any difference.


2 thoughts on “I just found out that 1 in 3 (!!!) people have a mutated gene

  1. Susan says:

    Hi, I work with Deplin. Thanks for sharing this information. Maybe I can provide some additional information on MTHFR and Deplin?

    Approximately 50% of the population is affected by the MTHFR polymorphism. There are 2 classifications- homozygous and heterozygous. Homozygous MTHFR is either CC or TT. Approximately 50% of the population is CC which is considered “normal”. These individuals have an ample amount of MTHFR enzyme and can easily process folic acid into L-methylfolate. Only about 10% of the population is TT. These individuals have less than 30% of the normal amount of MTHFR enzyme and they cannot process folic acid very effectively.The other 40% of the population is heterozygous or CT. They have approximately 70% of normal MTHFR enzyme levels.

    Approximately 70% of depressed patients are affected by the MTHFR polymorphism, which limits their ability to convert folic acid into L-methylfolate. Additionally, individuals of Hispanic and Mediterranean descent have twice the risk of this genetic problem.

    Just to give you some information on Deplin, it is not a supplement but a prescription medical food for the dietary management of suboptimal levels in depressed patients. Deplin is indicated as an adjunctive therapy to an antidepressant. Deplin contains L-methylfolate, and works through a natural process in the brain to manage the monamines associated with mood. You can find more information at http://www.deplin.com/

    I hope this information helps you and your readers.

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